GLP1Base
Menu

Side-by-side comparison

Semaglutide vs Tirzepatide

Semaglutide and tirzepatide are both approved medicines built on the GLP-1 hormone. Semaglutide acts on the GLP-1 receptor only; tirzepatide acts on both the GIP and GLP-1 receptors. They come from different companies and are sold under different brand names.

Last verified 2026-09-29 · how we verify

In plain English

The real difference

  • Semaglutide acts on the GLP-1 receptor. Tirzepatide acts on the GIP receptor and GLP-1 receptor.[src][src]
  • Both are approved medicines.[src][src]
  • Semaglutide is made by Novo Nordisk; tirzepatide by Eli Lilly.
  • Semaglutide is taken as a once-weekly injection or once-daily tablet; tirzepatide as a once-weekly injection.
  • Half-life (how long until half the drug has left the blood): Semaglutide, about 1 week (elimination half-life); the drug stays in the blood for about 5 weeks after the last injection; tirzepatide, about 5 days (5 to 6 days in adults with obesity).[src][src]
  • Our sources include a head-to-head trial of the two molecules. SURMOUNT-5 versus semaglutide: -20.2% with tirzepatide versus -13.7% with semaglutide at 72 weeks (751 adults, open-label).[src]

Which one suits a person is a decision for them and their clinician.

Semaglutide and Tirzepatide, side by side

Semaglutide compared with Tirzepatide
SemaglutideNovo NordiskTirzepatideEli Lilly
The basics
MoleculeSemaglutideTirzepatide
Brand namesOzempic, Wegovy, RybelsusMounjaro, Zepbound
MakerNovo NordiskEli Lilly
Acts onThe hormone receptors the drug switches onGLP-1 receptorGIP receptor, GLP-1 receptor
Approved to treat
  • Ozempic: Type 2 diabetes; lowering the risk of major heart events in adults with type 2 diabetes (injection: those with established heart disease; tablets: those at high risk); lowering kidney-disease and heart-death risk in adults with type 2 diabetes and chronic kidney disease (injection only)
  • Wegovy: Chronic weight management (injection from age 12; tablets in adults); lowering heart-event risk in adults with established heart disease and obesity or overweight (injection and tablets); noncirrhotic MASH with moderate to advanced fibrosis in adults (injection only, accelerated approval)
  • Rybelsus: Type 2 diabetes; lowering the risk of major heart events in adults with type 2 diabetes at high risk (oral tablet)
  • Mounjaro: Type 2 diabetes (adults and children 10 and older); reducing major cardiovascular events in adults with type 2 diabetes at high risk (US label)
  • Zepbound: Chronic weight management in adults with obesity, or overweight with a weight-related condition; moderate-to-severe obstructive sleep apnea in adults with obesity (US label)
How it is takenApproved as a once-weekly subcutaneous injection (Ozempic, Wegovy) or as a once-daily oral tablet co-formulated with SNAC (Rybelsus, Ozempic tablets, Wegovy tablets), prescribed and supervised by a clinician.Subcutaneous injection, given once a week, supplied as prefilled pens or vials
Half-lifeHow long until half the drug has left the bloodAbout 1 week (elimination half-life); the drug stays in the blood for about 5 weeks after the last injection[src]About 5 days (5 to 6 days in adults with obesity)[src]
Evidence and safety
Evidence levelSame for both
Approved. Approved by a major regulator after large trials.
Approvals and filings
  • FDA approval, Ozempic. Original FDA approval on 5 December 2017 (injection, type 2 diabetes).[src]
  • FDA approval, Wegovy. Original FDA approval on 4 June 2021 (injection, chronic weight management).[src]
  • FDA approval for MASH. On 15 August 2025 the FDA granted Wegovy accelerated approval for noncirrhotic MASH with moderate to advanced liver fibrosis; a study to confirm clinical benefit is ongoing.[src]
  • EMA authorisation, Ozempic. Authorised in the European Union on 8 February 2018 for type 2 diabetes.[src]
  • FDA approval for type 2 diabetes. Approved on 13 May 2022 as Mounjaro, to improve blood sugar control in adults with type 2 diabetes as an addition to diet and exercise.[src]
  • FDA approval for weight management. Approved on 8 November 2023 as Zepbound for chronic weight management in adults with obesity, or overweight with a weight-related condition.[src]
  • FDA approval for sleep apnea. Zepbound approved on 20 December 2024 for moderate-to-severe obstructive sleep apnea in adults with obesity.[src]
  • EU authorisation. Marketing authorisation for Mounjaro granted on 15 September 2022; the EU indications cover type 2 diabetes (adults and children 10 and older) and weight management in adults. Sleep apnea is not a separate EU indication.[src]
Key trial resultsTrials test the molecule, not a brand; each result names its population
  • STEP 1 weight result. Mean weight change at 68 weeks was -14.9% with semaglutide versus -2.4% with placebo (1,961 adults, plus lifestyle intervention).[src]
  • SELECT heart outcomes. Major cardiovascular events occurred in 6.5% on semaglutide versus 8.0% on placebo (hazard ratio 0.80; 17,604 adults with heart disease and overweight or obesity, no diabetes).[src]
  • SURMOUNT-1 weight change at 72 weeks. -20.9% at the highest of three maintenance doses versus -3.1% with placebo (2,539 adults with obesity, or overweight with a weight-related condition, and without diabetes).[src]
  • SURMOUNT-5 versus semaglutide. -20.2% with tirzepatide versus -13.7% with semaglutide at 72 weeks (751 adults, open-label).[src]
Known safety signals
  • Boxed warning: in rodents semaglutide caused dose- and duration-dependent thyroid C-cell tumours at clinically relevant exposures. Whether it does so in humans is unknown. It is contraindicated in people with a personal or family history of medullary thyroid carcinoma or with MEN 2.[src]
  • Gastrointestinal effects are the most common adverse reactions. In the pooled weight-management trials of Wegovy injection versus placebo, nausea occurred in 44% versus 16%, diarrhoea 30% versus 16%, vomiting 24% versus 6% and constipation 24% versus 11%.[src]
  • The label warns of acute pancreatitis, acute gallbladder disease (cholelithiasis in 1.6% of adults on Wegovy injection versus 0.7% on placebo in weight-reduction trials), acute kidney injury from volume depletion, and hypersensitivity reactions.[src]
  • In SUSTAIN-6, diabetic retinopathy complications were higher with semaglutide than placebo (hazard ratio 1.76; 95% CI 1.11 to 2.78) in people with type 2 diabetes at high cardiovascular risk.[src]
  • Because semaglutide delays gastric emptying, there are rare post-marketing reports of pulmonary aspiration during general anaesthesia or deep sedation in people taking GLP-1 receptor agonists.[src]
  • Compounded semaglutide products are not FDA-approved. As of 31 May 2026 the FDA had received 990 adverse-event reports associated with compounded semaglutide. The FDA notes these events are likely underreported, because federal law does not require state-licensed pharmacies that are not outsourcing facilities to report them.[src]
  • Boxed warning: in rats, tirzepatide caused thyroid C-cell tumours at clinically relevant exposures. It is unknown whether it causes these tumours, including medullary thyroid carcinoma, in humans. It is contraindicated in people with a personal or family history of medullary thyroid carcinoma or with Multiple Endocrine Neoplasia syndrome type 2.[src]
  • In SURPASS-2, the most common adverse events with tirzepatide were gastrointestinal and mostly mild to moderate: nausea in 17 to 22%, diarrhoea in 13 to 16% and vomiting in 6 to 10% of the three tirzepatide groups. Serious adverse events were reported in 5 to 7% of tirzepatide patients and 3% of semaglutide patients.[src]
  • US labels list nausea, diarrhoea, vomiting, constipation, abdominal pain and dyspepsia among the most common adverse reactions (5% or more of patients), and warn of serious gastrointestinal reactions (not recommended in severe gastroparesis), acute kidney injury from dehydration, acute gallbladder disease and acute pancreatitis.[src]
  • The label states that the risk of hypoglycaemia, including severe hypoglycaemia, is increased when tirzepatide is used with insulin or an insulin secretagogue such as a sulfonylurea.[src]
  • Because it delays gastric emptying, tirzepatide can affect the absorption of oral medicines, and there are rare postmarketing reports of pulmonary aspiration in people taking GLP-1 receptor agonists who had elective procedures under general anaesthesia or deep sedation.[src]
  • Other label warnings include serious hypersensitivity reactions (anaphylaxis, angioedema) reported after marketing, monitoring for diabetic retinopathy complications in people with type 2 diabetes and a history of retinopathy, and possible fetal harm in pregnancy.[src]
Legal status
United States
Approved

FDA-approved as Ozempic, Rybelsus and Wegovy; compounded copies lost their shortage cover in 2025 and 503B is proposing a formal exclusion[src]

Full detail →
Approved

FDA-approved as Mounjaro (type 2 diabetes) and Zepbound (weight management, sleep apnea); shortage over since December 2024[src]

Full detail →
United Kingdom
Approved

Licensed in the UK: Ozempic and Rybelsus for type 2 diabetes, Wegovy for weight management (now also as a tablet)[src]

Full detail →
Approved

Licensed in the UK as Mounjaro for type 2 diabetes and for weight management; NHS access is being phased in[src]

Full detail →
European Union
Approved

Authorised EU-wide for type 2 diabetes, weight management and MASH (Ozempic, Rybelsus, Wegovy, Kayshild)[src]

Full detail →
Approved

Authorised EU-wide as Mounjaro for type 2 diabetes and for weight management in adults[src]

Full detail →
Australia
Approved

Approved on the ARTG as Ozempic, Rybelsus and Wegovy. PBS covers Ozempic for type 2 diabetes; Wegovy is not yet PBS-listed. Compounded copies barred since 1 Oct 2024.[src]

Full detail →
Approved

Approved as Mounjaro for type 2 diabetes (Dec 2022) and weight management (Sep 2024). Not PBS-listed: the sponsor is not proceeding for now. Compounding barred since Oct 2024.[src]

Full detail →
Canada
Generics available

Approved as Ozempic, Rybelsus and Wegovy; generic semaglutide approved from April 2026 and on sale since May 2026[src]

Full detail →
Approved

Approved as Mounjaro (type 2 diabetes) and Zepbound (weight management, sleep apnea); no generic submissions[src]

Full detail →

Trial results come from separate studies unless a row says it is a head-to-head trial. Populations, durations and methods differ, so compare numbers across columns with care.

Go deeper

Molecule

Semaglutide explained →Watch the 3D body journey →

Molecule

Tirzepatide explained →Watch the 3D body journey →

Educational information only. Not medical advice, not a recommendation to use any substance, and not an offer to supply. Talk to a licensed clinician about your own care.

Sources (88)

  1. 01Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)New England Journal of Medicine (via PubMed) · 2021-03-18 · accessed 2026-09-29
  2. 02Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes (SUSTAIN-6)New England Journal of Medicine (via PubMed) · 2016-11-10 · accessed 2026-09-29
  3. 03Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT)New England Journal of Medicine (via PubMed) · 2023-12-14 · accessed 2026-09-29
  4. 04Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW)New England Journal of Medicine (via PubMed) · 2024-07-11 · accessed 2026-09-29
  5. 05Phase 3 Trial of Semaglutide in Metabolic Dysfunction-Associated Steatohepatitis (ESSENCE)New England Journal of Medicine (via PubMed) · 2025-06-05 · accessed 2026-09-29
  6. 06Drugs@FDA record, NDA 209637 (Ozempic): original approval 2017-12-05U.S. Food and Drug Administration (openFDA Drugs@FDA) · 2017-12-05 · accessed 2026-09-29
  7. 07Drugs@FDA record, NDA 213051 (Rybelsus): original approval 2019-09-20U.S. Food and Drug Administration (openFDA Drugs@FDA) · 2019-09-20 · accessed 2026-09-29
  8. 08Drugs@FDA record, NDA 215256 (Wegovy): original approval 2021-06-04U.S. Food and Drug Administration (openFDA Drugs@FDA) · 2021-06-04 · accessed 2026-09-29
  9. 09Drugs@FDA record, NDA 218316 (Wegovy tablets): original approval 2025-12-22U.S. Food and Drug Administration (openFDA Drugs@FDA) · 2025-12-22 · accessed 2026-09-29
  10. 10Wegovy approved by FDA for the treatment of adults with noncirrhotic MASH with moderate to advanced liver fibrosisNovo Nordisk (PR Newswire) · 2025-08-15 · accessed 2026-09-29
  11. 11Ozempic: EPAR (European public assessment report)European Medicines Agency · 2026-08 · accessed 2026-09-29
  12. 12Rybelsus: EPAR (European public assessment report)European Medicines Agency · 2026-04 · accessed 2026-09-29
  13. 13Wegovy: EPAR (European public assessment report)European Medicines Agency · 2026-09 · accessed 2026-09-29
  14. 14RYBELSUS and OZEMPIC (semaglutide) tablets: prescribing informationDailyMed (U.S. National Library of Medicine) / Novo Nordisk · 2026-01 · accessed 2026-09-29
  15. 15OZEMPIC (semaglutide) injection: prescribing informationDailyMed (U.S. National Library of Medicine) / Novo Nordisk · 2026-06 · accessed 2026-09-29
  16. 16WEGOVY (semaglutide) injection and tablets: prescribing informationDailyMed (U.S. National Library of Medicine) / Novo Nordisk · 2026-06 · accessed 2026-09-29
  17. 17FDA's concerns with unapproved GLP-1 drugs used for weight lossU.S. Food and Drug Administration · 2026-09-01 · accessed 2026-09-29
  18. 18OZEMPIC (semaglutide) injection prescribing informationU.S. Food and Drug Administration · 2026-05 · accessed 2026-09-29
  19. 19RYBELSUS / OZEMPIC (semaglutide) tablets prescribing informationU.S. Food and Drug Administration · 2026-07 · accessed 2026-09-29
  20. 20WEGOVY (semaglutide) injection and tablets prescribing informationU.S. Food and Drug Administration · 2026-09 · accessed 2026-09-29
  21. 21Novo Nordisk announcement: FDA approves the Wegovy pill (Form 6-K)Novo Nordisk A/S (SEC filing) · 2025-12-22 · accessed 2026-09-29
  22. 22FDA clarifies policies for compounders as national GLP-1 supply begins to stabilizeU.S. Food and Drug Administration · 2026-04-01 · accessed 2026-09-29
  23. 23List of Bulk Drug Substances for Which There Is a Clinical Need Under Section 503B (proposal not to include semaglutide, tirzepatide, liraglutide)Federal Register (FDA) · 2026-05-01 · accessed 2026-09-29
  24. 24GLP-1 medicines for weight loss and diabetes: what you need to knowMedicines and Healthcare products Regulatory Agency (MHRA) · 2026-02-05 · accessed 2026-09-29
  25. 25Single-dose 7.2mg semaglutide (Wegovy) pen approved to treat adult patients with obesityMedicines and Healthcare products Regulatory Agency (MHRA) · 2026-04-14 · accessed 2026-09-29
  26. 26First GLP-1 tablet for weight loss approved in the UKMedicines and Healthcare products Regulatory Agency (MHRA) · 2026-06-11 · accessed 2026-09-29
  27. 27Semaglutide (Wegovy) approved to treat form of liver diseaseMedicines and Healthcare products Regulatory Agency (MHRA) · 2026-07-03 · accessed 2026-09-29
  28. 28Semaglutide for managing overweight and obesity (TA875)National Institute for Health and Care Excellence (NICE) · 2023-03-08 · accessed 2026-09-29
  29. 29Kayshild: EPAR (European public assessment report)European Medicines Agency · 2026-04-09 · accessed 2026-09-29
  30. 30First oral GLP-1 treatment for weight managementEuropean Medicines Agency · 2026-05-22 · accessed 2026-09-29
  31. 31Applications for new human medicines under evaluation by the CHMP (September 2026)European Medicines Agency · 2026-09-04 · accessed 2026-09-29
  32. 32Obesite: prise en charge de Wegovy et Mounjaro a partir du 15 juin 2026, sous conditionsVidal · 2026-05-28 · accessed 2026-09-29
  33. 33Kyinsu: EPAR (European public assessment report)European Medicines Agency · 2026-02-12 · accessed 2026-09-29
  34. 34Arrêté du 23 mai 2026 modifiant la liste des spécialités pharmaceutiques remboursables aux assurés sociaux (WEGOVY)Légifrance, Journal officiel de la République française · 2026-05-28 · accessed 2026-09-29
  35. 35Arzneimittel-Richtlinie Anlage II: Lifestyle-Arzneimittel (Stand 20. August 2025)Gemeinsamer Bundesausschuss (G-BA) · 2025-08-20 · accessed 2026-09-29
  36. 36OZEMPIC semaglutide solution for injection pre-filled pen (ARTG 308324)Therapeutic Goods Administration (TGA) · 2019-08 · accessed 2026-09-29
  37. 37WEGOVY semaglutide solution for injection pre-filled pen (ARTG 356286)Therapeutic Goods Administration (TGA) · 2022-09 · accessed 2026-09-29
  38. 38RYBELSUS semaglutide tablet blister pack (ARTG 346198)Therapeutic Goods Administration (TGA) · 2022-02 · accessed 2026-09-29
  39. 39AusPAR: Wegovy (semaglutide), extension of indication (weight management in adolescents aged 12 and over; ARTG entry 29 February 2024)Therapeutic Goods Administration (TGA) · 2024-09-05 · accessed 2026-09-29
  40. 40PBS Medicines Status: semaglutide (Ozempic), type 2 diabetes mellitusAustralian Government Department of Health, Disability and Ageing (PBS) · 2026-03-31 · accessed 2026-09-29
  41. 41PBS Medicines Status: semaglutide (Wegovy), established cardiovascular disease with obesityAustralian Government Department of Health, Disability and Ageing (PBS) · 2026-07-23 · accessed 2026-09-29
  42. 42Manufacturing, supplying and advertising compounded medicines lawfullyTherapeutic Goods Administration (TGA) · 2026-05-14 · accessed 2026-09-29
  43. 43Prescription medicines under evaluation: Ozempic (semaglutide), claudication in peripheral arterial disease (accepted September 2025)Therapeutic Goods Administration (TGA) · 2025-09 · accessed 2026-09-29
  44. 44PBS Medicines Status: semaglutide (Wegovy), established atherosclerotic cardiovascular disease with obesity (November 2026 PBAC meeting)Australian Government Department of Health, Disability and Ageing (PBS) · 2026-07-23 · accessed 2026-09-29
  45. 45Drug Product Database API: active-ingredient search for semaglutideHealth Canada (Drug Product Database) · 2026-09-29 · accessed 2026-09-29
  46. 46Product Monograph: OZEMPIC (semaglutide injection)Novo Nordisk Canada Inc. · 2026-07-13 · accessed 2026-09-29
  47. 47Product Monograph: WEGOVY (semaglutide injection)Novo Nordisk Canada Inc. · 2025-12-10 · accessed 2026-09-29
  48. 48Canada approves second generic semaglutide, the first G7 country to do soHealth Canada · 2026-05-01 · accessed 2026-09-29
  49. 49Canada approves first generic semaglutide for weight lossHealth Canada · 2026-06-29 · accessed 2026-09-29
  50. 50Policy on Manufacturing and Compounding Drug Products in Canada (POL-0051)Health Canada · 2009-01-26 · accessed 2026-09-29
  51. 51Semaglutide + Pyridoxine: produced with an unauthorized active pharmaceutical ingredientHealth Canada · 2025-01-21 · accessed 2026-09-29
  52. 52Canada becomes the first G7 country to approve a generic version of semaglutideHealth Canada · 2026-04-28 · accessed 2026-09-29
  53. 53Semaglutide Injection: Incorrect Pen in Package (Type II recall, RA-82477)Health Canada · 2026-08-11 · accessed 2026-09-29
  54. 54Semaglutide Injection: Out-of-Specification (Impurity) (Type II recall, RA-82537)Health Canada · 2026-08-26 · accessed 2026-09-29
  55. 55Apo-Semaglutide Injection: Incorrect dose display (Type II recall, RA-82536)Health Canada · 2026-08-27 · accessed 2026-09-29
  56. 56Apo-Semaglutide Injection: Incorrect dose display (Type II recall, RA-82679)Health Canada · 2026-09-24 · accessed 2026-09-29
  57. 57Unauthorized health products sold online and seized at Rize Fitness may pose serious health risksHealth Canada · 2025-12-24 · accessed 2026-09-29
  58. 58Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)New England Journal of Medicine · 2022-07-21 · accessed 2026-09-29
  59. 59Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (SURPASS-2)New England Journal of Medicine · 2021-08-05 · accessed 2026-09-29
  60. 60Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5)New England Journal of Medicine · 2025-07-03 · accessed 2026-09-29
  61. 61Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA)New England Journal of Medicine · 2024-10-03 · accessed 2026-09-29
  62. 62Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity (SUMMIT)New England Journal of Medicine · 2025-01-30 · accessed 2026-09-29
  63. 63Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes (SURPASS-CVOT)New England Journal of Medicine · 2025-12-18 · accessed 2026-09-29
  64. 64MOUNJARO (tirzepatide) injection, prescribing informationU.S. National Library of Medicine (DailyMed), FDA-approved label · 2026-09 · accessed 2026-09-29
  65. 65ZEPBOUND (tirzepatide) injection, prescribing informationU.S. National Library of Medicine (DailyMed), FDA-approved label · 2026-09 · accessed 2026-09-29
  66. 66Drug Trials Snapshots: MOUNJAROU.S. Food and Drug Administration · 2023-06-13 · accessed 2026-09-29
  67. 67FDA Approves New Medication for Chronic Weight ManagementU.S. Food and Drug Administration · 2023-11-08 · accessed 2026-09-29
  68. 68FDA Approves First Medication for Obstructive Sleep ApneaU.S. Food and Drug Administration · 2024-12-20 · accessed 2026-09-29
  69. 69Mounjaro (tirzepatide): European public assessment reportEuropean Medicines Agency · 2022-09-15 · accessed 2026-09-29
  70. 70MOUNJARO (tirzepatide) injection prescribing informationU.S. Food and Drug Administration · 2026-09 · accessed 2026-09-29
  71. 71ZEPBOUND (tirzepatide) injection prescribing informationU.S. Food and Drug Administration · 2026-09 · accessed 2026-09-29
  72. 72MHRA authorises diabetes drug Mounjaro (tirzepatide) for weight management and weight lossMedicines and Healthcare products Regulatory Agency (MHRA) · 2023-11-08 · accessed 2026-09-29
  73. 73Tirzepatide for managing overweight and obesity (TA1026)National Institute for Health and Care Excellence (NICE) · 2024-12-23 · accessed 2026-09-29
  74. 74Mounjaro (tirzepatide) price increase: Drug Tariff redeterminationNHS Business Services Authority (NHSBSA) · 2025-09 · accessed 2026-09-29
  75. 75Fake Mounjaro (tirzepatide) KwikPen 15mg pre-filled pensMedicines and Healthcare products Regulatory Agency (MHRA) · 2026-02-24 · accessed 2026-09-29
  76. 76New diabetes and obesity medicines: an AIFA guideItalian Medicines Agency (AIFA) · 2026-05-18 · accessed 2026-09-29
  77. 77MOUNJARO tirzepatide solution for injection pre-filled pen (ARTG 379330)Therapeutic Goods Administration (TGA) · 2022-12 · accessed 2026-09-29
  78. 78AusPAR: Mounjaro (tirzepatide), new chemical entityTherapeutic Goods Administration (TGA) · 2023-11-16 · accessed 2026-09-29
  79. 79AusPAR: Mounjaro (tirzepatide), extension of indications (chronic weight management)Therapeutic Goods Administration (TGA) · 2024-09-26 · accessed 2026-09-29
  80. 80PBS Medicines Status: tirzepatide (Mounjaro), type 2 diabetes mellitusAustralian Government Department of Health, Disability and Ageing (PBS) · 2026-06-30 · accessed 2026-09-29
  81. 81Prescription medicines under evaluation: Mounjaro (tirzepatide), proposed use from age 10 (accepted September 2025)Therapeutic Goods Administration (TGA) · 2025-09 · accessed 2026-09-29
  82. 82Prescription medicines under evaluation: Mounjaro (tirzepatide), cardiovascular risk reduction (accepted December 2025)Therapeutic Goods Administration (TGA) · 2025-12 · accessed 2026-09-29
  83. 83Drug Product Database: ZEPBOUND product recordHealth Canada (Drug Product Database) · 2026-09 · accessed 2026-09-29
  84. 84Product Monograph: ZEPBOUND (tirzepatide injection)Eli Lilly Canada Inc. · 2026-06-11 · accessed 2026-09-29
  85. 85Product Monograph: MOUNJARO (tirzepatide injection)Eli Lilly Canada Inc. · 2026-06-23 · accessed 2026-09-29
  86. 86Generic submissions under review (list current as of 2026-08-31)Health Canada · 2026-08-31 · accessed 2026-09-29
  87. 87Unauthorized injectable peptide drugs seized and sold by Canada Peptide may pose serious health risksHealth Canada · 2025-08-01 · accessed 2026-09-29
  88. 88Thinking about buying GLP-1 drugs like Ozempic or Mounjaro? Beware of fake or unauthorized productsHealth Canada · 2026-01-21 · accessed 2026-09-29