European Medicines Agency (EMA) with the European Commission; national competent authorities in each member state
Is MOTS-c legal in European Union?
Not approvedNo EU marketing authorisation; named on the WADA 2026 prohibited list (S4.4.1)
Not approved as a medicine here.
MOTS-c has no EU marketing authorisation and is absent from the EMA dataset and Union Register. Under Article 6 of Directive 2001/83/EC, no medicine may be placed on the market without a marketing authorisation. WADA's 2026 Prohibited List names MOTS-c under S4.4.1 (metabolic modulators, AMPK activators), so it is banned in sport at all times.
Last verified 2026-09-29 · how we verify
MOTS-c elsewhere
Sources (3)
- 01EMA medicines data (JSON report): human and veterinary medicines, with authorisation statusEuropean Medicines Agency · 2026-09-29 · accessed 2026-09-29
- 02Directive 2001/83/EC on the Community code relating to medicinal products for human use (consolidated text, 1 January 2025)European Union (EUR-Lex) · 2025-01-01 · accessed 2026-09-29
- 03The 2026 Prohibited ListWorld Anti-Doping Agency · 2025-09 · accessed 2026-09-29