Gastric emptying

For experts

Gastric emptying is the movement of stomach contents into the small intestine. GLP-1 acts as an enterogastrone that inhibits gastric emptying, an effect that may be a dominant mechanism for its reduction of post-meal glucose excursions. US semaglutide labelling describes a minor delay in early post-meal gastric emptying, states that this may affect absorption of concomitant oral medicines, and notes rare post-marketing reports of pulmonary aspiration during anaesthesia or deep sedation.